Myositis ossificans progressiva (MOP)

Also known as fibrodysplasia ossificans progressiva, MOP is a condition where bone forms within muscles.

This bone tissue is generated as a result of faulty repair processes of damaged muscle tissue.

The bone formation is usually first noticed in early childhood as a series of hard lumps in the neck or along the spine. The lumps, which may be tender, gradually shrink in size as the affected muscles are replaced by bone. As this process progresses, it locks joints in place and makes movement difficult or impossible.

About 60 people in the UK have MOP.


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