We are pleased to announce that we are investing over £650,000 into seven Duchenne muscular dystrophy research projects that came out of our grant round. This was made possible thanks to the incredible support of families and other donors who support the Duchenne Research Breakthrough Fund (DRBF).
The projects were selected following a thorough peer review process using independent international experts, which included our Medical Research Committee. Our Lay Research Panel, which currently includes parents whose sons have Duchenne muscular dystrophy, was also part of the assessment process. This ensures we are funding the best quality science that is relevant to people with muscle-wasting conditions. Read more about how we fund research.
The seven new projects are:
- Reducing muscle scarring in Duchenne muscular dystrophy – Dr Linda Popplewell
- Is the activation of AMPK a potential treatment for Duchenne muscular dystrophy? – Professor Dominic Wells
- Assessing the feasibility of a new cell- and gene-based therapy for Duchenne muscular dystrophy – Professor Jenny Morgan
- Understanding the effects of Duchenne muscular dystrophy on heart function to improve gene therapy – Professor Jenny Morgan
- Assessing muscle fibrosis by MRI – Professor Volker Straub
- Making ‘mini-muscles’ to test potential treatments for Duchenne muscular dystrophy – Dr Francesco Saverio Tedesco
- Using novel MRI to study changes in bone health in Duchenne muscular dystrophy – Dr Jarod Wong
We were able to fund these projects thanks to the support of families and other donors who support the Duchenne Research Breakthrough Fund (DRBF). The aims of the DRBF are to fund the very best scientific research into Duchenne muscular dystrophy, to ensure the development of vital infrastructure for clinical trial readiness and to work with regulatory bodies and pharmaceutical companies to ensure patients have early access to emerging treatments.
Robert Meadowcroft, Chief Executive Officer of Muscular Dystrophy UK, said:
We’re delighted to be making this important announcement today, on World Duchenne Awareness Day. These projects will help to improve our understanding of Duchenne muscular dystrophy and how it could be targeted with effective treatments. Without the dedication and commitment of our supporters, we would not be able to fund this important research as we work to accelerate steps to potential treatments.
Manoj Thakrar, member of our Lay Research Panel and father of Shiv, who has Duchenne muscular dystrophy, said:
It is great to see the range of Duchenne research projects that have been funded as a result of the Muscular Dystrophy UK grant round. Research into all elements of Duchenne is vital to keep moving forward with the development of potential treatments.
It is only through your contributions that we can continue to fund the vital work that takes us closer to finding treatments for muscle-wasting conditions. Donate now and help to change the lives of thousands of people living with these conditions. Thank you for your support.