Studying biological mechanisms of drugs that increase utrophin levels

  • Prof Angela Russell

    Studying biological mechanisms of drugs that increase utrophin levels

    Dr Angela Russell and her PhD student will search for molecules showing therapeutic promise for Duchenne muscular dystrophy.

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  • Genome surgery for Duchenne muscular dystrophy

    Professor George Dickson and his team have developed an innovative technique with the potential to repair the genetic mutation that causes Duchenne muscular dystrophy.

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  • Developing gene therapy for Duchenne muscular dystrophy

    Professor George Dickson and his team plan to develop a novel gene therapy approach for Duchenne muscular dystrophy that is aimed at delivering a functional, full-size dystrophin gene to muscle cells using a harmless virus.

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  • Prof Dame Kay Davies

    Developing small molecules to target Duchenne muscular dystrophy

    Professor Dame Kay Davies and her colleagues aim to find drugs with the potential to increase levels of a protein called utrophin which could compensate for the lack of dystrophin seen in boys with Duchenne muscular dystrophy.

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  • Dr Lizzie Harris

    Investigating the genetic causes of limb girdle muscular dystrophies

    Dr Lizzie Harris is using next generation sequencing to find a genetic diagnosis for people with limb girdle and related muscular dystrophies.

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  • Discovering biomarkers for Duchenne muscular dystrophy

    Professor Wood’s project aims to identify molecules which could be used as biomarkers for Duchenne muscular dystrophy. They will also develop improved methods of detecting these molecules.

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  • Altering the muscle environment to influence stem cell behaviour

    In this project, Dr Jennifer Morgan will investigate new ways of improving the efficiency of stem cell transplants in muscle for people with Duchenne muscular dystrophy.

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