Limb girdle muscular dystrophy 2B (LGMD2B) is an autosomal recessive form of limb girdle muscular dystrophy (LGMD). The age of onset of muscle weakness is extremely variable, the most common age being between 20 and 30 years.
Life expectancy is generally within a normal range because the heart and breathing muscles are usually not affected.
In later stages of the condition, breathing difficulties can occur but are usually less severe than in other muscular dystrophies. These symptoms can include poor sleep, nightmares, tiredness or headaches after waking up in the morning, lack of appetite and falling asleep during the day.
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