Muscular Dystrophy UK is investing £1.2 million into 9 new research projects this year, bringing our total research portfolio to over £10m.
Some of these projects will investigate methods to improve the delivery of drugs, optimise the use of cough-assist devices and find out how many people are living with muscle-wasting conditions in the UK.
MDUK’s annual grant round sees expert researchers and people living with muscle-wasting conditions select the most relevant, high-quality research to fund. The charity is now funding 56 different projects in the UK and through international partnerships.
Dr Kate Adcock, Director of Research and Innovation at Muscular Dystrophy UK, said:
We are delighted to announce our new projects for 2019. These will increase our knowledge about a number of neuromuscular conditions, help us understand more about delivering treatments and provide an update on the number of people in the UK who are affected by neuromuscular conditions.
Over the past year, research that we have funded has demonstrated structural brain differences in individuals with adult-onset myotonic dystrophy, improved our understanding of the side effects of steroid treatments for Duchenne and showed that a common collagen VI mutation can be corrected using innovative genetic tools.
We look forward to following the progress of our new grants.
This year’s projects
- Professor Matthew Wood at the MDUK Oxford Neuromuscular Centre to develop a non-viral delivery method for microdystrophin gene therapy
- Dr Suzan Hammond at the MDUK Oxford Neuromuscular Centre to improve the delivery of molecular patches for spinal muscular atrophy
- Dr Patrick Murphy at Guy’s and St Thomas’ Hospitals to investigate the optimal settings for a cough-assist device
- Professor Pete Zammit at King’s College London to investigate how DUX4 and PAX7 contribute to muscle weakness in facioscapulohumeral muscular dystrophy
- Dr Iain Carey at St George’s University of London to investigate how many people in the UK have a form of muscle-wasting condition
- Dr Francesco Saverio Tedesco at University College London (UCL), who is making ‘mini-muscles’ to test genome editing for laminopathies
- Dr Federica Montanaro at UCL, who is investigating the role of dystrophin in the heart
- Dr Arianna Fornili at Queen Mary University of London, who is screening for molecules that alter myosin function
- Dr Yalda Jamshidi at St George’s University of London to identify new genetic causes of limb girdle muscular dystrophy
It is only through your contributions that we can continue to fund the vital work that takes us closer to finding treatments and cures for muscle-wasting conditions. Donate now and help change the lives of thousands of people living with these conditions. Thank you for your support.