Past research projects

Professor Nadir Maraldi and his team at the Rizzoli Orthapaedic Institute in Bologna are investigating whether a type of skin cell, called melanocytes, could be used as a cellular model to study collagen VI-related myopathies....

In this PhD studentship, Professor Peter Zammit and his student, Louise Moyle, explored the role that muscle stem cells have in facioscapulohumeral muscular dystrophy (FSH). They delivered the protein thought to cause FSH (DUX4) into muscle stem cells....

Exon skipping that restores the levels of dystrophin protein is currently in clinical trials for Duchenne muscular dystrophy....

In this project, Professor Richard Piercy and his team will study dogs with naturally occurring Duchenne muscular dystrophy which may offer benefits over other currently used animal models of the condition....

Clinical Research Fellow, Dr Hamilton and his team will investigate how the genetic changes that occur in myotonic dystrophy type 1 affect the severity of the brain-related symptoms associated with the condition such as impairment of thinking and excessive...

Biomarkers provide a non-invasive way of accurately monitoring progression of a condition and testing the effectiveness of potential treatments in clinical trials....

Professor Zammit and his team at King’s College London will generate a mouse model that will enable them to study the molecular mechanisms underlying facioscapulohumeral muscular dystrophy (FSHD)....

Dr Andrew Shevchuk and his team from Imperial College London will investigate how mutations associated with some types of centronuclear myopathy and Charcot-Marie-Tooth disease (CMT) affect an essential cell process called endocytosis that allows cells to ...

In this project, Professor Jenny Morgan and her team at University College, London used a mouse model to investigate a biological process that leads to muscle fibre death in Duchenne muscular dystrophy.

This project by Professor Tom Gillingwater at Edinburgh University is based on the observation that in mice with spinal muscular atrophy (SMA), some populations of motor neurones survive whereas others are lost....