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Overview

VCP disease refers to conditions caused by a mutation of the Valosin Containing Protein (VCP) gene.

It is inherited in an autosomal dominant manner and primarily presents as an adult-onset condition affecting muscle, bone and brain.

Another term for VCP disease is Inclusion Body Myopathy associated with Paget’s Disease of Bone and Frontotemporal Dementia (IBMPFD). A person with IBMPFD may have one, two or all of the following:

  • Inclusion Body Myopathy (IBM)
  • Paget’s Disease of Bone (PDB)
  • Frontotemporal Dementia (FTD)

While there is an approved treatment for Paget’s Disease of Bone, unfortunately there are no known treatments for Inclusion Body Myopathy or Frontotemporal Dementia.

For more information on VCP disease, please visit Cure VCP Disease’s website.

Types of VCP disease

Symptoms

Symptoms section content

Causes

Causes section content

Diagnosis

Diagnosis section content

Treatment

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