LGMD2I is caused by mutations in the Fukutin-related protein gene (FKRP), which gives instructions to produce a protein important to the muscle fibres.
Mutations in the FKRP also cause a form of severe congenital muscular dystrophy (MDC1C).
Download your alert card
Alert cards are conveniently shaped to fit inside a wallet and outline key recommendations and precautions that a non-specialist clinician would need to know during a time of worsening health.