ACTA1 – This gene produces a protein called α- actin. Mutations in this gene account for around 15 to 25 percent of cases. Errors in this gene are inherited in an autosomal dominant or autosomal recessive pattern.
NEM2 – The product of this gene is a protein called nebulin. It is thought that mutations in this gene are a common cause of nemaline myopathy but definite statistics are unavailable. Mutations in this gene are inherited in an autosomal recessive pattern.
TPM3 – The product of this gene is a protein called α- Tropomyosin 3. Mutations in this gene account for only two to three percent of affected individuals, and are inherited in an autosomal dominant or autosomal recessive pattern.
TPM2 – This gene encodes a protein called β-Tropomyosin. Only very few individuals have been identified with errors in this gene. Inheritance is in an autosomal dominant pattern.
TNNT1 – This gene produces a protein called Troponin 1. Errors in this gene have only been identified in a population of Old Order Amish individuals. Inheritance is in an autosomal recessive pattern.