Physiotherapy can slow the progression of contractures. An initial physiotherapy assessment at the time of the diagnosis should be followed by regular exercise and check-ups. The main aim of physiotherapy is to keep the muscles as active as possible and to prevent or slow the progression of joint contractures. People with SEPN1-related myopathy are encouraged to remain as active as possible; swimming is a particularly good form of exercise.
Occupational therapists can also help by providing orthoses, such as splints, long leg callipers and a wheelchair as necessary.
If curvature of the spine (scoliosis) occurs, a spinal brace may help to improve posture and delay deterioration of the curvature. In some cases, surgical intervention (scoliosis surgery) may be needed.
Children and adults with SEPN1-related myopathy should ideally be followed regularly in a specialist neuromuscular clinic. This would give them access to physiotherapy, orthotic, respiratory, orthopaedic, spinal and genetic specialists as needed.