Looking back at our impact 2024-2025

5 November 2025

As we launch our 2024/2025 Impact Report, our Chief Executive Andy Fletcher reflects on the accomplishments, successes and significant milestones we’ve achieved together over the last year.

Today I’m delighted to publish our latest Impact Report.  A year in which we’ve continued to increase the impact of our research, services and influencing work.

I was delighted to join the charity as Chief Executive in November 2024 and I’ve enjoyed getting to know the charity and meeting our extraordinary community.

Funding groundbreaking research

In 2024/25, we continued to fund groundbreaking research into a range of muscle wasting conditions. We were delighted to commit significant funding to the LifeArc Centre for Rare Mitochondrial Diseases, as well as to three projects focused on developing treatments for congenital muscular dystrophy, as part of our strategic partnership. And, following a new strategic grant round, a £1m award to Professor Mary Reilly at University College London to develop a new scanning method to spot small changes in Charcot- Marie-Tooth disease (CMT).

As part of our regular grant round, we funded a further 12 projects with a lifetime funding commitment of £1.7m. This brought the number of our live research programmes to 45, focusing on 25 different conditions. These grants, alongside our strategic research investment, show our commitment to funding innovative programmes designed to better understand and treat muscle wasting conditions for the benefit of our community.

Making treatments available

After research and clinical trials comes access to treatments, and this too has accelerated at pace since the first treatment for a muscle wasting condition became available in the UK in 2016. This year, we were delighted to have helped secure the approval of Vamorolone, a new treatment for Duchenne muscular dystrophy. We were also involved in a further eight NHS treatment appraisals that could potentially benefit our community.

Living well

As well as funding research to give hope for the future, we also continue to provide direct support to people with muscle wasting conditions so they can live their life fully today.

This year we supported more than 3,300 people through our helpline, and provided equipment grants to 131 people living with a muscle wasting condition. Our peer-to-peer support network also continues to grow and thrive.

This year, we continued to support and influence the NHS and the development of neuromuscular services, and speak up for our community.

Our conferences for Allied Health Professionals and Care Advisers had more than 170 in-person attendees and our upskilling webinars continued to grow and attract professionals from across health and care services.

Raising awareness

We were delighted that our wonderful garden at the RHS Chelsea Flower Show exceeded all our expectations. The unique opportunity presented by Project Giving Back for a fully funded garden at the RHS Chelsea Flower Show 2024 culminated in winning Best in Show. The garden allowed us to reach people who had never heard of muscle wasting conditions, to give our community a voice, and to raise awareness of our work.

While we live in uncertain times, we are committed to continuing to grow our impact to ensure that people living with muscle wasting conditions have the support they need.

During the past year we have been developing a new, bold and ambitious strategy to lead our work over the next decade. This was launched in September 2025.

Thank you

We finish this year once again proud of our wonderful community. Our research partners, support services and funders, volunteers, fundraisers, staff and trustees.

Thank you for your support, your involvement, your stories, your requests and your continued passion to make our charity matter, because we all know how much our muscles matter.